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(44) was about 20% higher than the maximum in the previously published results of our study (12), a faster cortisol-induced down-regulation of APR could have resulted in an earlier reduction of IL-6

Clin Pharmacol Ther 1991;50:695-701

Use only clinician-supervised, reputable sources

they should not be self-administered

However, during APAP overdose, the excessive production of NAPQI overwhelms the cellular antioxidant capacity, leading to the accumulation of NAPQI-protein adducts